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Steroid-Free Nasal Spray Demonstrated Seasonal Allergy Symptom Improvement Within 15 Minutes In Clinical Study

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The prescription antihistamine (azelastine HCl) Nasal Spray relieved the major symptoms of pollen allergy, including sneezing, runny nose and congestion, within 15 minutes of application compared to placebo and maintained efficacy at all time points for 8 hours in a randomized, single dose, double-blind, placebo- controlled study.

In addition, a group of patients treated with intranasal mometasone furoate monohydrate (a moderately potent glucocorticoid) did not show symptom improvement compared to placebo during the eight hour study period. Data from the 450-patient study, conducted in a controlled environmental exposure unit (EEU), were presented at the 2007 American Academy of Allergy, Asthma and Immunology (AAAAI) Annual Meeting in San Diego, California.”Patients suffering from seasonal allergies want rapid relief from their symptoms. These new data confirm that the second-generation antihistamine nasal spray ASTELIN is fast-acting and maintains significant control of moderate to severe allergy symptoms,” said William E. Berger, MD, Clinical Professor, Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, and Medical Director of Allergy and Asthma Associates of Southern California. “Because azelastine HCl rapidly relieves the full range of rhinitis symptoms, including congestion, caused by both seasonal allergens and environmental irritants, and is well-tolerated, it is a particularly effective first-line therapy for most patients.”(Source: American Academy of Allergy, Asthma and Immunology (AAAAI) Annual Meeting : University of California, Irvine : March 2007.)


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Posted On: 8 March, 2007
Modified On: 16 September, 2014

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