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New study shows link between gastro-oesophageal reflux disease (GORD) and work productivity

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Gastro-oesophageal reflux disease (also known as GORD, gastroesophageal reflux disease, GERD or acid reflux disease) is a condition with a particularly high level of disruption to the lives of sufferers in terms of symptoms, activities of daily living and employment.1 A recent study published by the American College of Occupational and Environmental Medicine investigated the link between the incidence of GORD and employees’ attendance and productivity. The findings of the study reveal that GORD is associated with a significant increase in employee’s work absence and a significant decrease in both hourly and annual productivity.4 

GORD is a disease of the distal oesophagus and stomach. It involves the inflammation and damage of the lower oesophageal mucosa due to the spontaneous and involuntary reflux of gastric contents, including ingested food, gastric acid and occasionally pancreatic and biliary secretions.2,3  

Previous studies on the association between GORD and absences from work have reported that work interference stems from symptoms that disturb sleep and cause daytime tiredness.5 This latest study is the first to examine the associations between GORD, absences and productivity using objective data and specific analysis techniques.

The case-control study measured work absences and on-the-job productivity in a sample of approximately 350,000 employees from several large, national employers in the United States. The researchers examined claims data, including health care, prescription drug, absence, disability and workers compensation data together with employee demographic and payroll data. 

The findings of the study reveal that GORD is associated with a significant increase in employee’s work absence and a significant decrease in both hourly and annual productivity.  Compared to employees without GORD, employees with GORD had an average of:4

  • 41% more sick leave days
  • 59% more short-term disability days
  • 39% more long-term disability days
  • 48% more workers’ compensation days
  • 4.4% lower objective productivity per hour worked; and
  • 6.0% lower annual objective productivity.

The results of the study highlight both an area of concern for employers and an opportunity for improvement of disease management which could lead to improved work productivity.

Proton pump inhibitors are used to relieve symptoms of GORD as they supress acid production in the stomach.8 One PPI example is pantoprazole (Somac) can be administered intravenously or orally.9 It is an effective treatment for GORD by blocking the gastric acid secretion pump as it has a longer duration of action10 and provides faster symptomatic relief.11


References

  1. Hellier MD, Williams JG. The burden of gastrointestinal disease: implications for the provision of care in the UK. Gut 2007; 56; 165-166. Available from online at URL: http://gut.bmj.com/cgi/content/full/56/2/165 
  2. Ip S, Bonis P, Tatsioni A, et al. Comparative effectiveness of management strategies for gastroesophageal reflux disease. Evidence Report/Technology Assessment No. 1. (Prepared by Tufts-New England Medical Center Evidence-Based Practice Center under Contract No. 290-02-0022.) Rockville, Md: Agency for Healthcare Research and Quality. December 2005. Available online at URL: http://effectivehealthcare.ahrq.gov/repFiles/GERD Final Report.pdf
  3. Robinson MJ, Robertson DM. Practical Paediatrics. 5th edition. Churchill Livingstone, 2003.
  4. Wahlqvist P, Brook R, Campbell S, et al. Objective measurement of work absence and on-the-job productivity: a case-control study of US employees with and without gastroesophageal reflux disease. Journal of Occupational and Environmental Medicine. 2008; 50; 25-31.
  5. Liker H, Jones R, Ducrotte P. The effect of sleep disturbance due to gastroesophageal reflux disease on work and leisure productivity: results from a multinational survey. Gastroenterology. 2005; 128 (4 Suppl 2): A386.
  6. Thomson ABR. The concept of complete remission of gastro-oesophageal reflux disease comparative efficacy of pantoprazole and esomeprazole using the ReQuestTM questionnaire, Clin Drug Invest 2007; 27(10): 663-672.
  7. Orr W. Eur J of Gastroenterol & Hepatol 2005; 17:113–120
  8. Richter JE, Fraga P and Mack M et al. Prevention of erosive oesophagitis relapse with pantoprazole. Ailment Pharmacol Ther 2004; 20: 567-575
  9. Somac Injection, MIMS database [online] Last Updated: 30/11/2006. Available from: URL: http://mims.hcn.net.au
  10. Shin JM, Sachs G. Differences in binding properties of two proton pump inhibitors on the gastric H+, K+-ATPase in vivo. Biochemical Pharmacology 2004 68: 2117-2127
  11. Scholten T, Gatz G and Hole U. Once-daily pantoprazole 40mg and esomeprazole 40mg have equivalent overall efficacy in relieving GERD-related symptoms. Ailment Phamacol Ther 2003; 18: 597-594

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Dates

Posted On: 24 April, 2008
Modified On: 11 March, 2014

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