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Generic Name: Ranitidine hydrochloride
Product Name: Zantac


The use of Ranitidine is indicated in the following conditions:

  • Peptic ulcer disease
  • Gastro-oesophageal reflux disease
  • Heartburn


Zantac belongs to a class of drugs called histamine receptor antagonists. Its active ingredient, Ranitidine, works by decreasing the amount of acid the stomach produces.

Dose advice

Peptic Ulcer Disease:

  • The initial recommended dose is 300 mg orally given as a single evening dose for 4–8 weeks or 50 mg intravenously or intramuscularly given every 6–8 hours.
  • Maintenance dosing is 150–300 mg orally given as a single evening dose.

Gastro-Oesophageal Reflux Disease:

  • 300 mg orally given as a single evening dose

Prevention of stress ulcer:

  • The initial dose is 50 mg intravenously given slowly
  • An intravenous infusion of 125–250 micrograms/kg/hour should be continued until risk factors for stress ulcer are removed.


  • 150 mg orally twice a day for 4–8 weeks.


  • 2–4 mg/kg orally twice daily up to a maximum dose of 300 mg a day. 1 mg/kg intravenously every 6–8 hours up to a maximum dose of 50 mg.



Common side effects

Uncommon side effects

  • Development of breast tissue in males
  • Decreased libido
  • Impotence
  • Reversible involuntary movement

For further information talk to your doctor.

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Posted On: 22 July, 2003
Modified On: 15 May, 2008


Created by: myVMC