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Difflam Gel

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Generic Name: Benzydamine
Product Name: Difflam Gel


Difflam Gel can be used for the temporary (up to two weeks) relief of pain and inflammation that may occur in acute soft tissue injuries such as sprains, strains, sports injuries (eg. tennis elbow), tendonitis and bursitis.


Difflam Gel contains the active ingredient benzydamine. Benzydamine belongs to a family of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs). They work to reduce pain and inflammation in the body by reducing the production of hormone-like substances that promote the inflammatory response.

Benzydamine does not treat the underlying cause of the inflammation, however, and should not be used for extended periods of time without medical advice. Benzydamine also possesses local anaesthetic activity.

Dose advice

  • Difflam Gel should be massaged lightly into the affected area 3-6 times daily as required or as directed by the doctor
  • Difflam Gel should not be used for a period of more than 14 days of uninterrupted treatment without medical consultation
  • Difflam Gel is not suitable for treating bruises
  • Never apply Difflam Gel to an open wound or on skin that has a rash or infection
  • Avoid contact with eyes and mucosal surfaces (such as the mouth, vagina and inside the nose) to prevent irritation
  • Seek medical advice before using Difflam Gel if you have had a previous allergic reaction to aspirin or other NSAIDs – symptoms of an allergic reaction may include:
    • Asthma, wheezing or shortness of breath
    • Swelling of the face, lips or tongue, causing difficulty swallowing and breathing
    • Hives, itching or skin rash
    • Fainting
  • Difflam Gel should be used only under medical advice in patients who are pregnant (ADEC category B2) or breast feeding



Common side effects

Difflam Gel is well tolerated. Difflam Gel may cause local skin reactions in less than 2% of patients, including contact dermatitis (itchy, red and scaly skin) or photosensitivity (increased susceptibility to sun burn and irritation from sunlight).

Consult your doctor if you experience any of the above symptoms, or any other unusual or abnormal symptoms that concern you.


  1. MIMS Online. [Monograph online] MIMS Australia Pty Ltd 2003. [Cited December 23, 2007]
  2. Australian Medicines Handbook 2007, Adelaide, Pharmaceutical Society of Australia, 2007.

For further information talk to your doctor.

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Posted On: 2 January, 2008
Modified On: 1 February, 2008
Reviewed On: 16 January, 2008

Created by: myVMC