Are you a Health Professional? Jump over to the doctors only platform. Click Here


Print Friendly, PDF & Email

Generic Name: Promethazine theoclate
Product Name: Avomine


Avomine is used in the prevention and treatment of motion sickness. It has also been used in the treatment of nausea and vomiting due to other causes, including:

  • Gastroenteritis (eg. food poisoning)
  • Vestibular disorders
  • Drug intolerance
  • Migraine
  • Infectious diseases
  • Radiation therapy


Promethazine is an antihistamine agent. It blocks histamine receptors in the stomach to prevent nausea and vomiting due to a number of causes. It also has sedative and other effects that may contribute to its anti-nausea effect.

Dose advice


Travel sickness prevention:

  • Long journeys: Take one tablet at bedtime each night beginning the night before the journey commences.
  • Short journeys: Take one tablet 1-2 hours before the journey commences.

Treatment of travel sickness:

  • Take one tablet immediately and another that same evening.
  • Take a third tablet on the following evening.
  • Additional tablets can be taken when needed.
  • More than 4 tablets in 24 hours is unlikely to be necessary.

Nausea and vomiting due to other causes:

  • Take one tablet and repeat as required.
  • 1 tablet at bedtime is often sufficient.
  • No more than 4-6 tablets should be taken in 24 hours.


3-5 years:

  • One quarter of the corresponding adult dose.

5-10 years:

  • Half of the corresponding adult dose.

Over 10 years:

  • Corresponding adult dose.


10’s: S2 30’s: S3

Common side effects

Uncommon side effects

  • Changes in heart rate or rhythm
  • Faintness
  • Palpitations
  • Low blood pressure
  • Skin rash
  • Photosensitivity
  • Hives
  • Jaundice
  • Tremor
  • Changes in muscle tone
  • Uncontrolled muscle movements
  • Tinnitus
  • Euphoria
  • Nervousness
  • Insomnia
  • Seizures
  • Irregular breathing
  • headache
  • Urinary retention.

For further information talk to your doctor.

Print Friendly, PDF & Email


Posted On: 22 July, 2003
Modified On: 18 March, 2016

Created by: myVMC