Avomine

Generic Name: Promethazine theoclate
Product Name: Avomine

Indication

Avomine is used in the prevention and treatment of motion sickness. It has also been used in the treatment of nausea and vomiting due to other causes, including:

• Gastroenteritis (eg. food poisoning)
• Vestibular disorders
• Drug intolerance
• Migraine
• Infectious diseases
• Radiation therapy

Action

Promethazine is an antihistamine agent. It blocks histamine receptors in the stomach to prevent nausea and vomiting due to a number of causes. It also has sedative and other effects that may contribute to its anti-nausea effect.

Dose advice

Adults

Travel sickness prevention:

• Long journeys: Take one tablet at bedtime each night beginning the night before the journey commences.
• Short journeys: Take one tablet 1-2 hours before the journey commences.

Treatment of travel sickness:

• Take one tablet immediately and another that same evening.
• Take a third tablet on the following evening.
• Additional tablets can be taken when needed.
• More than 4 tablets in 24 hours is unlikely to be necessary.

Nausea and vomiting due to other causes:

• Take one tablet and repeat as required.
• 1 tablet at bedtime is often sufficient.
• No more than 4-6 tablets should be taken in 24 hours.

Children

3-5 years:

• One quarter of the corresponding adult dose.

5-10 years:

• Half of the corresponding adult dose.

Over 10 years:

• Corresponding adult dose.

Schedule

10’s: S2 30’s: S3

Common side effects

• Dry mouth
• appetite loss
• Stomach upset
• Nausea
• Vomiting
• Diarrhoea
• Constipation
• Sedation
• Restlessness
• Weakness
• Incoordination
• Fatigue
• Blurred vision.

Uncommon side effects

• Changes in heart rate or rhythm
• Faintness
• Palpitations
• Low blood pressure
• Skin rash
• Photosensitivity
• Hives
• Jaundice
• Tremor
• Changes in muscle tone
• Uncontrolled muscle movements
• Tinnitus
• Euphoria
• Nervousness
• Insomnia
• Seizures
• Irregular breathing
• headache
• Urinary retention.

For further information talk to your doctor.