Aprinox
Generic Name: Bendrofluazide
Product Name: Aprinox
Indication
Bendrofluazide is used for the treatment of oedema (swelling of the body) due to heart failure, liver disease, drugs, the menstrual cycle and other causes. It is also used to treat mild to moderate cases of high blood pressure.
Action
Bendrofluazide is a diuretic that reduces the reabsorption of fluid and salt in the kidneys resulting in increased loss of salt and water from the body. In people who are oedematous (have extra unnecessary fluid in their body) Bendrofluazide will remove the fluid. By causing water and salt loss Bendrofluazide also helps to decrease the blood pressure.
Dose advice
For treatment for oedema
5 to 10 mg is given daily, or on alternate days. This should be reduced to a maintenance dose of 5 to 10 mg one to three times a week as the oedema resolves.
For the treatment of premenstrual tension
5 mg is given daily for the 5 to 7 days preceding the onset of menses.
For the treatment of hypertension
the standard dosing is 5 mg once daily however dosing ranges from 2.5 – 10 mg daily. Antihypertensive effect is not increased be giving doses greater than 10 mg.
Schedule
S4
Common side effects
- Dizziness
- Weakness
- Muscle cramps
- Polyuria
- Orthostatic hypotension
- Hyponatremia
- Hypokalemia
- Hyperuricemia
- Hypochloremic alkalosis
- Hypomagnesemia
Uncommon side effects
- Rash
- Hyperglycaemia
- Hyperlipidemia
- Hypercalcemia
- Blurred vision
- Impotence
- Nausea, vomiting, diarrhoea and constipation
- Purpura
- Dermatitis
- Urticaria
- Photosensitivity
For further information talk to your doctor.
Dates
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