Subutex
Generic Name: Buprenorphine hydrochloride
Product Name: Subutex
Indication
- Maintenance of opioid dependence
- Opioid withdrawal
Action
Buprenorphine is a partial opioid receptor agonist. Reduces withdrawal symptoms and craving for opioids in opioid dependence
Dose advice
Buprenorphine maintenance:
- Initial dose 4mg sublingual in the morning; an additional 2-4mg may be given in the afternoon on the first day.
- Increase daily dose by 2-4mg at 1-3 day intervals, depending on withdrawal symptoms and tolerance of adverse effects.
Usual maintenance range:
- 12-24mg daily
Opioid withdrawal:
- Dose and length of treatment is tailored according to severity of withdrawal symptoms and tolerance of adverse effects.
- Typical withdrawal regimens use an initial dose of 4-8mg daily, reducing over 5-8 days to zero
Administration instructions:
- Place tablet under tongue until dissolved- takes 2-10 minutes
Schedule
S8
Common side effects
Adverse effects may be difficult to distinguish from mild opioid withdrawal:
- Constipation
- Dyspepsia
- Hypotension
- Nausea
- Vomiting
Uncommon side effects
- Bradycardia
- Severe itching
For further information talk to your doctor.
Dates
Tags
Created by: