Generic Name: Dacarbazine
Product Name: D.T.I.C
Dacarbazine interferes with cellular replication by forming cross-linkages between DNA strands.
Specialist protocols should be consulted concerning dosages:Melanoma:- An initial dose that may be used is 250 mg/m2 daily given by intravenous infusion on days 1-5 of each 21-day cycle. – Alternatively, 800 mg/m2 can be given on day 1 of each 21-day cycle.- These doses may be used in single or combination therapy.- Subsequent doses depend on the individual patient’s response and the severity of adverse effects.Hodgkin’s disease:- Dacarbazine is used in combination treatment with other antineoplastic agents.- 150 mg/m2 each day given by intravenous infusion on days 1?5 of each 28-day cycle.- Alternatively, 375 mg/m2 can be given on day 1 and day 15 of each 28-day cycle.
Common side effects
Uncommon side effects
For further information talk to your doctor.