The goal of this study is to find an effective and well-tolerated medical therapy for itching due to liver disease. Persons with primary biliary cirrhosis or chronic hepatitis C are currently being enrolled in the study. Persons participating in the study are given sertraline, a medication which is also often used for depression,to treat their itching. The dose is gradually increased as the effect on itching and any other potential side effects are carefully monitored.
Official Title
Conditions
– Pruritus- Liver Cirrhosis, Biliary- Hepatitis C
Study Type
Interventional
Study Design
Treatment, Non-Randomized, Open Label, Dose Comparison, Single Group Assignment, Safety/Efficacy Study
Further Details
Study Start
Eligibility & Criteria
Ages Eligible for Study: 21 Years – 80 Years, Genders Eligible for Study: Both Criteria Itching for at least 3 months Primary biliary cirrhosis or hepatitis C Elevated alkaline phosphatase for at least 6 months
Total Enrolment
40
Contact Details
[1] National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (US)All content and media on the HealthEngine Blog is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. Always seek the guidance of your doctor or other qualified health professional with any questions you may have regarding your health or a medical condition. Never disregard the advice of a medical professional, or delay in seeking it because of something you have read on this Website. If you think you may have a medical emergency, call your doctor, go to the nearest hospital emergency department, or call the emergency services immediately.
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