Perioperative stress response in infants undergoing cardiac surgery: a comparison of three alfentanil dosage regimens

Official Title

Conditions

Study Type

Study Design

Further Details

What is the smallest dose of alfentanil that minimises neuro-hormonal stress response in infants undergoing cardiac surgery? 90 infants aged less than 1 year undergoing palliative or corrective surgery of congenital cardiac defects involving cardiopulmonary bypass. Patients will be given one of three alfentanil dose regimens by random allocation. Serial blood sampling will be used to provide plasma for analysis of markers of neuro-hormonal response.

Study Start

Eligibility & Criteria

Total Enrolment

90

Contact Details

(source: NHS Trusts Clinical Trials Register, Feb 2004)

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