This protocol concerns the approach to the localization, diagnosis of MEN1 and management of the tumor and the tissue samples in patients with Zollinger-Ellison syndrome. It details the diagnostic imaging tests to be used to localize the tumor, investigations for MEN1 the subsequent management of the tumor and tissue samples for research.

Official Title

Evaluation of the Gastrinoma in Patients with Zollinger-Ellison Syndrome

Conditions

– Gastrinoma- Zollinger Ellison Syndrome

Study Type

Observational

Study Design

Natural History

Further Details

This protocol concerns the approach to tumor localization, diagnosis of MEN1 and management of the tumor and the tissue samples in patients with Zollinger-Ellison syndrome. It details the diagnostic imaging tests to be used to localize the tumor, investigations for MEN1 the subsequent management of the tumor and tissue samples for research.

Study Start

Eligibility & Criteria

Genders Eligible for Study: Both Criteria INCLUSION CRITERIA:New patients will be evaluated initially as described in the protocol entitled, “Diagnostic evaluation of patients with suspected abnormalities of gastric secretion” (89-DK-0005).Only those patients that are being treated under the protocol entitled, “Medical Therapy of Zollinger-Ellison Syndrome” (protocol # 89-DK-0015) will be entered into this tumor localization and management protocol.

Total Enrolment

999

Contact Details

[1] National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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