The purpose of this study is to examine the effects of a physiological bolus of growth hormone on insulin signaling pathways in muscle tissue in healthy lean men.

Official Title

The Effect of a Physiological Bolus of Growth Hormone (GH) on Insulin Signaling Pathways in Muscle Tissue From Healthy Adults

Conditions

  • Insulin Resistance

Study Type

Interventional

Study Design

Basic Science, Randomised, Single Blind (Subject), Placebo Control, Factorial Assignment.

Further Details

Primary Outcome Measures:

  • PI3-kinase activity i muscle tissue

Secondary Outcome Measures:

  • Growth Hormone Signaling Proteins in Muscle Tissue and other Insulin Signaling Proteins in Muscle Tissue.

Study Start

May 2007

Eligibility & Criteria

Eligibility:

  • Ages Eligible for Study: 18 Years to 30 Years
  • Genders Eligible for Study: Male
  • Accepts Healthy Volunteers: Yes

Inclusion Criteria:

  • Male
  • Healthy
  • Age between 18 and 30 years
  • BMI ≤ 26

Exclusion Criteria:

  • Known present disease including diabetes mellitus
  • BMI > 26
  • Uses any medication
  • Consumes > 21 units of alcohol per week

Total Enrolment

8

Contact Details

Denmark Department M (endocrinology and diabetes)    
Aarhus, Denmark, 8000

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