This study will evaluate a new and safe testing method for identifying medicines that can cause problems in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals. We are looking for volunteers with G6PD deficiency who would be willing to donate blood samples.

Official Title

A Test to Predict the Hemolytic Potential of Drugs in G6PD Deficiency

Conditions

glucose-6-phosphate dehydrogenase (G6PD)

Study Type

Interventional

Study Design

Prevention, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Pharmacodynamics Study

Further Details

Study Start

Eligibility & Criteria

Ages Eligible for Study: 18 Years – 60 Years, Genders Eligible for Study: BothAccepts Healthy VolunteersCriteria * Not pregnant or planning pregnancy * Have not taken any anti-malarial medication in past month * Negative blood tests for HIV and specific types of hepatitis * Not allergic to primaquine * Need both G6PD-deficient volunteers and G6PD-normal volunteers

Total Enrolment

Expected Total Enrollment: 14

Contact Details

Walter Reed Army Institute of Research (WRAIR)

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