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Bigger bodies bringing more cancers

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Growing obesity levels are increasing the burden of cancers throughout the world, say University of Queensland researchers.

UQ School of Population Health researcher Dr Nirmala Pandeya and colleagues at the International Agency for Research on Cancerestimate that a quarter of all obesity-related cancers in 2012 could be attributed to the rising average body mass index since 1982.

“We found that about 3.6% of the cancers worldwide – or nearly half a million new cancer cases a year – were caused by excess body weight,” Dr Pandeya said.

“In Australia, the percentage is similar, with 3.4% of all cancers in men (2350 new cases) and 7.4% (3782 new cases) in women diagnosed in 2012 attributable to overweight and obesity.”

Researchers looked specifically at cancers where being overweight or obese is a proven risk factor.

“Of these cancers, we found that, for men, 23% of kidney cancers, 19% of colon cancer and 13% of pancreatic cancer could be attributed to excess weight.”

Dr Pandeya said the impact was more pronounced in women.


“Post-menopausal breast cancer and endometrial cancer were responsible for more than 60% of cancers due to obesity in women diagnosed in Australia in 2012,” she said.

“That’s more than 2000 cases.”

According to the latest figure, about 63% of Australians are overweight or obese.

Using estimates of the number of overweight and obese people in the population and the proven increased risk of cancer, researchers determined how many new cancer cases could be attributed to the world’s increasing body mass index levels, which have doubled since 1980.

The global study found that the burden of cancer was strongest in the developed world, with the US leading the way.

Dr Pandeya said the findings highlighted the need for more concerted efforts to curtail the rates of overweight and obesity.

“Other important risk factors for cancer, such as smoking, are declining, but we see the proportion of overweight and obese men and women still rising in most countries,” she said.


“If this trend continues we are likely to see an increasing number of people diagnosed with cancers that could have been avoided by maintaining a healthy weight.”

Dr Pandeya is joint lead author, with IARC’s Dr Melina Arnold, on the research paper, which is published in The Lancet: Oncology.

(Source: The University of QueenslandThe Lancet: Oncology)


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Dates

Posted On: 8 December, 2014
Modified On: 17 December, 2014

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