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Predictors of Drug Hypersensitivity in HIV Infected Subjects

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A case-control study to look at hypersensitive and tolerant individuals matched for HLA genetic predisposition, when considering predictors of drug hypersensitivity.The study aims to identify the immunological factors increasing the risk of drug reactions in HIV positive individuals.

Official Title

Predictors of Drug Hypersensitivity in HIV Infected Subjects

Conditions

HIV Infections Hypersensitivity

Study Type

Observational

Study Design

Screening, Cross-Sectional, Case Control, Retrospective/Prospective Study

Further Details

Study Start

August 2005; Expected completion: August 2008

Eligibility & Criteria

  • Ages Eligible for Study: 18 Years and above
  • Genders Eligible for Study: Both

Inclusion Criteria:

  • HIV infected patients on treatment with the drugs Efavirenz, Nevirapine, or Abacavir.
  • Age over 18 Cases are those who have had a hypersensitivity reaction, and controls are those who have had no reaction

Total Enrolment

800

Contact Details

Alfred Hospital, Melbourne, Victoria, 3004, Australia; Recruiting

  • Dr Paul Cameron: 0061 3 9207 1449, Paul.Cameron@med.monash.edu.au
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Dates

Posted On: 1 January, 2013
Modified On: 16 September, 2014

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Created by: myVMC