Potential Allergens in Wine: Double-Blind Placebo-Controlled Trial

This study is designed to identify whether wines which are produced using the common potential food allergens such as proteins derived from fish, milk or egg are likely to contain sufficient food allergens to cause allergic reactions in susceptible individuals.

Official Title

Potential Allergens in Wine: Double Blind Placebo-Controlled Trial and Basophil Activation Analysis

Conditions

• Food Allergy
• Anaphylaxis

Study Type

Interventional

Study Design

Diagnostic, Randomised, Double-Blind, Placebo Control, Crossover Assignment, Safety Study

Further Details

Primary Outcome Measures:

• Allergic reactions to wine

Secondary Outcome Measures: 

• Positive basophil activation test to wines

Study Start

August 2002

Eligibility & Criteria

Official Title

Potential Allergens in Wine: Double Blind Placebo-Controlled Trial and Basophil Activation Analysis

Conditions

• Food Allergy
• Anaphylaxis

Study Type

Interventional

Study Design

Diagnostic, Randomised, Double-Blind, Placebo Control, Crossover Assignment, Safety Study

Further Details

Primary Outcome Measures:

• Allergic reactions to wine

Secondary Outcome Measures: 

• Positive basophil activation test to wines

Study Start

August 2002

Eligibility & Criteria

Eligibility

• Ages Eligible for Study: 18 Years to 65 Years
• Genders Eligible for Study: Both
• Accepts Healthy Volunteers: Yes

Criteria

Inclusion Criteria:

• Individuals with IgE-mediated food allergy to milk, fish, egg or nuts Otherwise no major medical problems Able to drink wine –

Exclusion Criteria:

• Major asthma or cardiac disease Unwilling or unable to participate

Total Enrolment

40

Contact Details

Please refer to this study by its ClinicalTrials.gov identifier: NCT00163735

Contacts

Contact: Robyn E O’Hehir, MBBS FRACP PhD      ++613 9276 2251      r.ohehir@alfred.org.au    

Locations

Australia, Victoria
 AIR Med, Alfred Hospital      Recruiting
       Melbourne, Victoria, Australia, 3004
       Contact: Robyn E OHehir, MBBS PhD FRACP     ++6139276 2251     r.ohehir@alfred.org.au    

       Principal Investigator: Robyn E O’Hehir, MBBS FRACP PhD            

Sponsors and Collaborators

Bayside Health

The Australian Wine Research Institute, Adelaide

National Health and Medical Research Council, Australia

The Alfred

Investigators

Study Director:      Robyn E O’Hehir, MBBS PhD FRACP      Alfred Hospital and Monash University

Principal Investigator:      Jennifer M Rolland, PhD      Monash University

Principal Investigator:      Creina S Stockley, PhD      The Australian Wine Research Institute

Total Enrolment

40

Contact Details

Please refer to this study by its ClinicalTrials.gov identifier: NCT00163735

Contacts

Contact: Robyn E O’Hehir, MBBS FRACP PhD      ++613 9276 2251      r.ohehir@alfred.org.au    

Locations

Australia, Victoria
 AIR Med, Alfred Hospital      Recruiting
       Melbourne, Victoria, Australia, 3004
       Contact: Robyn E OHehir, MBBS PhD FRACP     ++6139276 2251     r.ohehir@alfred.org.au    

       Principal Investigator: Robyn E O’Hehir, MBBS FRACP PhD            

Sponsors and Collaborators

Bayside Health

The Australian Wine Research Institute, Adelaide

National Health and Medical Research Council, Australia

The Alfred

Investigators

Study Director:      Robyn E O’Hehir, MBBS PhD FRACP      Alfred Hospital and Monash University

Principal Investigator:      Jennifer M Rolland, PhD      Monash University

Principal Investigator:      Creina S Stockley, PhD      The Australian Wine Research Institute