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Pulmicort Turbuhaler/Repsules

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Generic Name: Budesonide
Product Name: Pulmicort Turbuhaler/Repsules

Indication

  • Maintenance treatment in persistent asthma.
  • Croup (acute laryngotracheobronchitis) (nebulised budesonide only).

Action

Reduce bronchial mucosal inflammation and bronchial hyper-reactivity.

Dose advice

Asthma in Adults:

  • MDI /DPI 100-400micrograms twice daily (once daily dosing possible up to 400micrograms lately); up to 2000 micrograms daily in severe persistent asthma.
  • Neb: 0.5-1 mg twice daily.

Asthma in Children:

  • MDI /DPI 50-200 micrograms twice daily; up to 1600 micrograms daily in severe persistent asthma.
  • Neb: 0.25-0.5 mg twice daily (nebulisation of budesonide requires a high flow nebuliser- 8L/min).

Croup:

  • Neb: 2mg as a single dose (nebulisation of budesonide requires a high flow nebuliser- 8L/min).

Pregnancy:

  • Limited experience but asthma control is paramount; ADEC category- B3.

Lactation:


  • Limited experience, should be safe to use.

Schedule

S4

Common side effects

  • Dysphonia
  • Oropharyngeal candidiasis
  • Facial skin irritation following nebulization

Uncommon side effects

  • Allergic reactions including bronchospasm, rash, urticaria, and angioedema.
  • Occurrence of systemic adverse effects depends on amount of systemic absorption, which is influenced by dosage, duration of treatment and delivery system used.
  • Adrenal impairment: may occur with high doses.
  • Bone density loss: clinical implications concerning the risk of osteoporosis and fracture are still unknown.
  • Glaucoma, cataract: risk may be increased.
  • Skin thinning and bruising: may occur with high doses.
  • Impaired growth: inhaled corticosteroids may reduce growth velocity mainly in the first year of treatment; effect on growth of other organs (e.g. brain and lung) is not well known; poorly controlled asthma may also cause growth retardation.

For further information talk to your doctor.


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Dates

Posted On: 22 July, 2003
Modified On: 31 October, 2015

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Created by: myVMC