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Pro-Banthine

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Generic Name: Propantheline bromide
Product Name: Pro-Banthine

Indication

Pro-Banthine is used to help in the treatment of peptic ulcer disease of both the stomach and duodenum. It is also useful for the treatment of a number of bladder problems including:

  • malfunction of the nerves controlling bladder emptying
  • urinary incontinence due to overactivity of the bladder-emptying muscle

Due to its ability to reduce sweat production, Pro-Banthine is also used to treat excessive perspiration.

Action

Pro-Banthine contains an agent that slows down and relaxes various aspects of the gastrointestinal system by blocking a chemical called acetylcholine. Acetylcholine is a substance used by many nerves to transmit messages, and Pro-Banthine works on the peripheral nerves that use it. The drug cannot cross the blood-brain barrier so no effects are seen in the central nervous system. Pro-Banthine reduces secretion of a number of substances, importantly gastric acid. It also reduces saliva and sweat secretion. Acetylcholine is also important in promoting the movement of the gastrointestinal system, so Pro-Banthine is useful in slowing that down too, as well as relaxing any spasm that may be occurring.

Dose advice

Peptic ulcer

  • 1 tablet three times a day, 30 minutes before each meal plus two tablets at bedtime
  • individual variation is significant, and often depends on the side effects experienced by the patient
  • maximum daily dose should not exceed 120mg.

Other indications:

  • 1-2 tablets three to four times daily

Schedule

S4


Common side effects

Side effects of Pro-Banthine are generally dose-related and reversible on stopping the drug. Some common side effects include:

  • dry mouth
  • blurred vision
  • thirst
  • urinary retention
  • tachycardia
  • constipation

Uncommon side effects

Some more uncommon side effects include:

  • loss of taste
  • headache
  • dizziness
  • nausea
  • vomiting
  • insomnia

For further information talk to your doctor.


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Dates

Posted On: 22 July, 2003
Modified On: 1 January, 1970


Created by: myVMC