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Generic Name: Dipyridamole
Product Name: Persantin


Persantin is used in patients with artificial heart valves to prevent the formation of unwanted blood clots after operations. It is used in combination with other anti-clotting medications.


  • Platelets are blood cells that contribute to clot formation. Persantin prevents clot formation by preventing platelets from sticking to one another, particularly in patients with hypercoagulability (that is, patients who form clots more frequently than is normal).
  • Persantin also causes the coronary artery, which supplies the heart muscle, to dilate.

Dose advice

The usual dose is 100 mg four times daily. Persantin should be taken one hour before eating.



Common side effects

  • The following side effects are considered common. They are usually mild and short-lived and do not usually warrant stopping the medication.
  • Headache, which may be severe.
  • Nausea, vomiting, stomach upset, diarrhoea.
  • Muscular aches.
  • Dizziness.
  • Flushing of the face.
  • Persantin may also cause:
  • Low blood pressure.
  • Hot flushes.
  • Fast heart rate.
  • Worsening of coronary artery disease, including angina.

Uncommon side effects

  • Uncommon side effects include:
  • The incorporation of dipyridamole into gallstones.
  • Thrombocytopaenia (lower than normal levels of platelets in the blood)
  • Hypersensitivity – rash, itchy red areas of swelling on the skin and possibly swelling of the lips and tissues around the eyes and airway spasm.
  • Excessive bleeding during or after an operation (rare).

For further information talk to your doctor.

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Posted On: 22 July, 2003
Modified On: 25 April, 2016

Created by: myVMC