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Generic Name: Esomeprazole magnesium trihydrate
Product Name: Nexium


Nexium is used for different conditions:

  • Gastro-oesophageal reflux disease (GORD)
    • This occurs when acid in the stomach washes back into the food pipe.
  • Treatment or prevention of gastrointestinal symptoms caused by NSAIDs.
  • Helicobacter pylori related ulcers (in combination with antibiotics)
    • This is an ulcer caused by a bacterium called helicobacter pylori. Nexium and the antibiotics work together to eradicate the bacteria and allow the ulcer to heal.


Nexium contains esomeprazole.

Esomeprazole works by reducing the amount of acid produced by the stomach, giving relief from the symptoms and allowing time for the ulcer to heal.

Dose advice

It is important you notify your doctor if you are planning to become or are currently pregnant (Nexium is ADEC Pregnancy Category B3) or are breastfeeding.

It is also important that you notify your doctor if you have any health conditions or are taking any other medications as your doctor may need to examine the risks and benefits of using this medication for you.

The tablets should be taken whole without crushing or chewing them. However, if you have swallowing difficulties, place the tablet in a glass of water until it breaks into pellets. Mix well and drink the liquid with pellets immediately or within 30 minutes.

Take the dose at the same time each day to obtain the best effect, and to help you remember to take it.

Nexium is only available via prescription from your doctor.


Schedule 4

Common side effects

All medicines have side effects. Some can be serious, but the most common ones are mild. Common side effects occurring in more than 1% of patients prescribed Nexium include:

Consult your doctor if you experience any side effects.

Uncommon side effects

These side effects occur in less than 1% of patients. Do not be alarmed by this list;  a patient will not necessarily experience any of these:

Consult your doctor if you experience any of the above symptoms, or any other unusual or abnormal symptoms that concern you.


  1. Australian Medicines Handbook. Esomeprazole. [Monograph online]AMH Pty Ltd 2007. [Cited December 17, 2007]. Available from:
  2. Nexium. MIMS Online. [Monograph online] MIMS Australia Pty Ltd 2007. [Cited December 17, 2007]. Available from: http://www.mims/
  3. Lazo, J, Gilman A, Brunton L, Parker K. Goodman & Gilman’s the pharmacological basis of therapeutics.11th ed. New York: McGraw-Hill; 2005

For further information talk to your doctor.

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Posted On: 22 July, 2003
Modified On: 24 January, 2008
Reviewed On: 7 January, 2008


Created by: myVMC