Navane

Generic Name: Thiothixene
Product Name: Navane

Indication

Treatment of acute and chronic psychoses.

Action

Antagonise D2 receptors resulting in anti-psychotic effects, including relief from symptoms such as hallucinations, delusions or abnormal behaviour/thought.

Dose advice

• Initially, 6-10mg/day in 2 or 3 divided doses.
• Maintenance 10-30mg once daily or in divided doses.
• Maximum 50mg daily.

Schedule

S4

Common side effects

• Anticholinergic effects: dry mouth, blurred vision, constipation, tachycardia, urinary hesitancy, increased intraocular pressure, nausea, sexual adverse effects.
• Orthostatic hypotension
• Sedation
• Extrapyramidal effects (Parkinsonism, Akathisia, Dystonias, Tardive Dyskinesia)
• Hyperprolactinaemia (may result in galactorrhoea, gynaecomastia, amenorrhoea or infertility)

Uncommon side effects

• Allergic reactions
• Pigmentary changes of skin or eyes
• Corneal and lens opacities
• Hypothermia
• Hyperthermia
• SIADH

For further information talk to your doctor.