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Naprosyn

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Generic Name: Naproxen
Product Name: Naprosyn

Indication

Naprosyn belongs to a group of drugs called nonsteroidal anti-inflammatory drugs. It is an anti-inflammatory drug used for the treatment of conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhoea, acute or chronic pain states and acute migraine. Naprosyn also reduces fever.

Action

Naproxen belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is an enzyme that is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury or certain diseases and cause pain, swelling and inflammation. As Naprosyn stops the production of prostaglandins, it is effective at relieving pain and inflammation.

All the medicines in this group reduce inflammation caused by the body’s own immune system and are effective pain killers.

Dose advice

Naprosyn should be taken with food.

Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis:

  • An initial dose of greater than or equal to 500mg daily in 2 divided doses.
  • Maintenance dose of 375-1000mg daily in 2 divided doses, to a maximum of 1000mg/day.

Acute pain states:

  • An initial dose of 500mg; then 250mg every 6-8hours to a maximum of 1250mg/day.

Dysmenorrhoea:

  • An initial dose of 500mg; then 250mg every 6-8hours to a maximum of 1250mg/day.

Acute migraine:

  • An initial dose of 750mg at the first sign of migraine, then 250-500mg as necessary (at a minimum of 1 hour after first dose) to a maximum of 1250mg/day.

Juvenile Rheumatoid arthritis:

  • 10mg/kg/day in 2 doses (every 12 hours).

Schedule

S4

Common side effects

Uncommon side effects

  • Palpitations
  • Hearing and visual disturbances
  • Depression
  • Yellowing of the eyes and skin
  • Gastrointestinal bleeding
  • Insomnia
  • Impaired concentration
  • Muscle weakness
  • Menstrual irregularities
  • Chills and fever

For further information talk to your doctor.

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Dates

Posted On: 22 July, 2003
Modified On: 1 January, 1970

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Created by: myVMC