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MS Mono

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Generic Name: Morphine sulfate
Product Name: MS Mono


Morphine is indicated in for the following:

  • Relief of moderate to severe acute and chronic pain
  • Cough suppression
  • Relief of severe shortness of breathing in patients with lung cancer
  • Treatment of pulmonary oedema
  • Treatment of diarrhoea


Morphine is an opioid medication. Opioids act on opioid receptors in the nervous system to reduce the sensation of pain. As well as relieving pain, Morphine also decreases breathing and causes constipation

Dose advice

Patients should be given the lowest dose of morphine, which will keep them free of pain at all times. Dose adjustments should be based on the patient degree of pain relief.

The capsules should be taken at 24 hourly intervals.


  • The dose given to an individual patient will depend on age, weight, and severity of pain, medical history and previous pain medications.
  • The usually initial dose in a patient presenting with severe pain is 60 mg a day. Increasing severity of pain will require an increased dosage of MS Mono.
  • Elderly patients may require dose reductions


  • Children weighing over 25kg: The initial recommended dose for chronic severe pain in cancer is 0.4 to 1.6 mg/kg per day
  • The dose will need to be adjusted depending on the patients clinical response



Common side effects

  • Nausea and vomiting
  • Drowsiness
  • Dry mouth
  • Dizziness and light-headedness when moving form a lying to standing position
  • Difficulty urinating
  • Constipation with prolonged use
  • Constriction of pupils

Uncommon side effects

  • Confusion
  • Hallucinations
  • Hives
  • Itching
  • Hypothermia
  • Slowing or speeding up of the heart rate
  • Abdominal pain
  • Rigid muscles
  • Flushing

For further information talk to your doctor.

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Posted On: 22 July, 2003
Modified On: 1 January, 1970


Created by: myVMC