Generic Name: Metoprolol tartrate
Product Name: Metohexal
- Myocardial infarction
- Prevention of migraine
- Atenolol, a type of beta-1-selective-beta-Blocker, competitively blocks beta- adrenoceptors in the heart, peripheral vasculature, bronchi, pancreas, uterus, kidney, brain and liver.
- The antihypertensive effect works by reducing cardiac output without reflex increase in peripheral vascular resistance; CNS effect and reduced renin secretionmay also contribute.
- The antianginal effect is due to reductionin left ventricular work and oxygen use, resulting from decrease in heart rate and contractility.
- The antiarrhythmic properties are due to antisympathetic effects: depression of sinus node function and atrio-ventricular conduction and prolongation of atrial refractory periods.
- Atenolol, a beta-1-selective blocker, has a higher affinity for beta-1 receptors in the heart with less effect on beta-2 receptorsin bronchi and peripheral vasculature.
- Oral: initially 50-100mg once daily for 1 Week; maintenance 50-100mg once or twice daily
- Oral: initially 25-50mg twice daily; maintenance 50-100mg 2-3 times daily
- Oral: 50-100mg 2-3 times dailyIV: 5mg (1mg/minute), repeated at 5 Minute intervals up to a maximum of 20mg
- Initially, IV 5mg at 5 minute intervals to a total of 15mg, then 25-50mg orally every 6 hours for 48 hours
Prevention of migraine
- Oral: 50-75mg twice daily
Common side effects
- Cold extremities
- Exacerbation of Raynaud’s Syndrome
- Heart failure
- Heart block
- Abnormal vision
- Decreased concentration
- Altered glucose and lipid metabolism
Uncommon side effects
- Exacerbation of psoriasis
- Muscle cramp
- Acute urinary retention
- Nasal congestion
- Hypersensitivity reaction
- Thrombocytopenic purpura
- Liver function abnormality
- Cardiac arrest
- Hepatic injury
For further information talk to your doctor.