Mesasal

Generic Name: Mesalazine
Product Name: Mesasal

Indication

Mesalazine is used in the treatment of:

• Acute inflammatory large bowel disease.
• Acute mild and moderate ulcerative colitis.
• Maintenance treatment of colitis.

Action

Mesalazine has a local anti-inflammatory action on the bowel wall, however, its exact mechanism of action is unknown.

Dose advice

Adults:– 250-500 mg orally taken three times a day.

Children:The initial recommended dose is 15-20 mg/kg orally three times a day. Maintenance treatment is with 10 mg/kg 2-3 times a day. Mesalazine is safe to use during pregnancy and lactation.

Hepatic impairment: Mesalazine is hepatically cleared and should be used with caution in patients with severe hepatic impairment.

Schedule

S4

Common side effects

• Nausea
• Rash
• Headache
• Diarrhoea.

Uncommon side effects

• Nerve damage
• Blood abnormalities
• Pancreatitis
• Kidney inflammation
• Hepatitis.

For further information talk to your doctor.