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Melleril

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Generic Name: Thioridazine; Thioridazine hydrochloride
Product Name: Melleril

Indication

Melleril is used to treat psychotic disorders unresponsive to at least 2 other antipsychotics.

Action

Antagonise D2 receptors resulting in anti-psychotic effects, including relief from symptoms such as hallucinations, delusions or abnormal behaviour/thought.

Dose advice

Adult:

  • 50-600mg daily in 3 divided doses. Maximum 800mg daily for up to 4 weeks.

Schedule

S4

Common side effects

  • Anticholinergic effects: dry mouth, blurred vision, constipation, tachycardia, urinary hesitancy, increased intraocular pressure, nausea, sexual adverse effects.
  • Orthostatic hypotension
  • Sedation
  • Extrapyramidal effects (Parkinsonism, Akathisia, Dystonias, Tardive Dyskinesia)
  • Hyperprolactinaemia (may result in galactorrhoea, gynaecomastia, amenorrhoea or infertility)

Uncommon side effects

For further information talk to your doctor.

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Dates

Posted On: 22 July, 2003
Modified On: 9 May, 2006

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