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Cefkor CD

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Generic Name: Cefaclor monohydrate
Product Name: Cefkor CD

Indication

Used in the treatment of infectious in adults (and children > 12 years) caused by pathogens susceptible to Cofactor. Including:

  • Lower respiratory infections (e.g. community acquired pneumonia, acute bronchitis and exacerbations of chronic bronchitis)
  • Upper respiratory tract infections (e.g. pharyngitis, tonsillitis, acute bacterial sinusitis)
  • Lower urinary tract infections
  • Skin and connective tissue structure infections.

Action

Microbiology

  • Cefaclor is a cephalosporin antibiotic with bactericidal activity. It is active against a variety of bacteria responsible for common infections, including some bacteria that are resistant to penicillin and other cephalosporin antibiotics.

Pharmacokinetics

  • Cefkor is well absorbed from the gut and peak plasma levels are achieved in close to 2 hours. When taken with food, the time taken to peak plasma levels increases, though the degree of absorption also increases.
  • Cefaclor is not metabolised.
  • Plasma half live in healthy patients is about 50 minutes.

Dose advice

Adults

Standard dosage: 375 mg. Twice daily.

Pneumonia, acute bacterial sinusitis: 750 mg, twice daily.

Renal impairment: Administer with caution in patients with severe renal impairment, though dosage adjustments are not usually required.

Use in pregnancy: (Category B1) Safety has not been established. Avoid the use of Cefkor in women of childbearing potential unless its use is considered essential.

Use in lactation: Small amounts of cefaclor are excreted in breast milk. Use with caution in breastfeeding women.

Children

Safety and efficacy have not been studied.

Schedule

S4

Common side effects

Uncommon side effects

As above

For further information talk to your doctor.

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Dates

Posted On: 22 July, 2003
Modified On: 1 January, 1970

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