Capurate

Generic Name: Allopurinol
Product Name: Capurate

Indication

Allopurinol is used in the following conditions
Treatment and long term control of gout
Certain types of kidney stones
Kidney disease caused by increased uric acid levels in the urine
In patients undergoing chemotherapy or radiotherapy

Action

Allopurinol reduces the production of uric acid. If uric acid is present in the body in excessive levels it can produce gout and kidney disease. Certain drugs given in chemotherapy can also increase uric acid levels.

Dose advice

Adults

The initial recommended dose is 100 mg once a day
This dose may be increased by 100 mg per day each month depending on how the patient responds to treatment
The usual dose ranges from 100â??300 mg per day

Patients with kidney disease may require different doses

Patients undergoing chemotherapy
Adults: 600â??800 mg per day given for 2â??3 days before chemotherapy commences. The dose may then be reduced depending on how the patient responds to treatment
Children: 10â??20 mg/kg per day given as one or two divided doses. A maximum dose of 600 mg per day should not be exceeded.