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Arima

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Generic Name: Moclobemide
Product Name: Arima

Indication

Major depression
Panic disorder
Social phobia

Action

Competitive and reversible inhibition of monoamine oxidase (MAO). It is relatively selective for type A (MAO-A). Synaptic concentrations of serotonin, noradrenaline, and dopamine are increased.
Full activity of the MAO-A enzyme is restored within 24-48 hours of stopping the drug
When used at higher than recommended doses, moclobemide will also inhibit MAO-B (dietary restrictions would then be warranted)

Dose advice

Initially 300mg daily in 1 or 2 divided doses, increasing after 2 weeks.
Maintenance 450-600mg daily in 1 or 2 divided doses.
Usual maximum dose 600mg daily

Schedule

S4

Common side effects

Nausea
Dry mouth
Constipation
Diarrhoea
Anxiety
Restlessness
Insomnia
Dizziness
Headache

Uncommon side effects

Visual disturbances
Gastrointestinal complaints (feeling of fullness)
Rash
Itch
Urticaria
Flushing
Rare:
Sedation

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For further information talk to your doctor.

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Dates

Posted On: 22 July, 2003
Modified On: 1 January, 1970


Created by: myVMC