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Generic Name: Amiloride hydrochloride, Hydrochlorothiazide
Product Name: Amizide


Amizide is used in the treatment of fluid retention due to heart or liver failure and is also used to reduce high blood pressure.


Amizide contains two drugs amiloride hydrochloride and hydrochlorothiazide. Hydrochlorothiazide increases water and salt loss from the kidneys relieving fluid retention and lowering the blood pressure. Hydrochlorothiazide can cause excessive loss of potassium from the kidneys and the Amiloride’s main action is to conserve potassium by reducing its loss from the kidneys.

Dose advice

Fluid retention due to heart failure

  • Dosing should start at 1-2 tablets daily and may be increased if necessary.


  • The initial dose is 1-2 tablets, given once a day or in two divided doses. This dose may be increased if necessary.

Fluid retention due to liver failure

  • Initial dosage is 1 tablet daily and this dose may be increased if necessary.
  • Dosing should never exceed 4 tablets per day



Common side effects

Uncommon side effects

  • Dizziness or lightheadedness when getting up from a lying or sitting position
  • Increased sensitivity of skin to sunlight
  • Constipation
  • Muscle aches
  • Impotence
  • Increased urination at night
  • Incontinence
  • Fainting
  • Rash

For further information talk to your doctor.

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Posted On: 22 July, 2003
Modified On: 25 April, 2016

Created by: myVMC