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Aldazine

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Generic Name: Thioridazine hydrochloride
Product Name: Aldazine

Indication

Psychotic disorders unresponsive to at least 2 other antipsychotics

Action

Antagonise D2 receptors resulting in anti-psychotic effects, including relief from symptoms such as hallucinations, delusions or abnormal behaviour/thought

Dose advice

Adult: 50-600mg daily in 3 divided doses. Maximum 800mg daily for up to 4 weeks

Schedule

Schedule 4

Common side effects

  • Anticholinergic effects: dry mouth, blurred vision, constipation, tachycardia, urinary hesitancy, increased intraocular pressure, nausea, sexual adverse effects
  • Orthostatic hypotension
  • Sedation
  • Extrapyramidal effects (Parkinsonism, Akathisia, Dystonias, Tardive dyskinesia)
  • Hyperprolactinaemia (may result in galactorrhoea, gynaecomastia, amenorrhoea or infertility)

Uncommon side effects

Allergic reactions Pigmentary changes of skin or eyes Corneal and lens opacities Hypothermia Hyperthermia SIADH

For further information talk to your doctor.

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Dates

Posted On: 22 July, 2003
Modified On: 3 April, 2008

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