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Acihexal

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Generic Name: Aciclovir
Product Name: Acihexal

Indication

Acyclovir is an antiviral agent which is active against types 1 and 2 of herpes simplex virus and varicella zoster virus.

Acyclovir is used for the following:

  • Treatment of a first episode of genital herpes
  • Management of recurrent episodes of genital herpes in certain patients.
  • Treatment of shingles when the rash has been present for less than 72 hours.
  • The management of patients with advanced HIV disease.

 

Action

 

  • Acyclovir is an antiviral agent which is active against types 1 and 2 of herpes simplex virus and varicella zoster virus.
  • Acyclovir prevents the virus from replicating in the cell and thus precents it from infecting more cells in the body.

 

Dose advice

First episode of genital herpes:

  • 200 mg every four hours while awake resulting in a total of 1000mg a day.
  • This dose should be continued for ten days.

Suppressive therapy for recurrent genital herpes:

  • 200 mg three times daily for six months.
  • After 6 months Acyclovir should be ceased.

Intermittent therapy for recurrent genital herpes:

  • 200 mg every four hours while awake resulting in a total of 1000mg a day.
  • This dose should be continued for five days.
  • Acyclovir should started as soon as signs or symptoms of a recurrent episode appear.

Herpes Zoster:

  • 800 mg five times daily at four hour intervals
  • Treatment should start as soon as possible after the rash appears
  • This dose should be continued for seven days.
  • For shingles with eye involvement therapy should be continued for seven to ten days

Advanced HIV disease:

  • 800 mg four times daily at six hour intervals for 12 months. Doses may required adjustment in patients with reduced kidney function.

 

Schedule

Schedule 4

Common side effects

 

 

Uncommon side effects

 

 

For further information talk to your doctor.

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Dates

Posted On: 22 July, 2003
Modified On: 4 March, 2008

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Created by: myVMC