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Tritace

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Generic Name: Ramipril
Product Name: Tritace

Indication

Tritace is a medication which belongs to a group of medicines called Angiotensin converting enzyme (ACE) inhibitors. Tritace is used to treat:

  • High blood pressure
  • Certain heart conditions for instance heart failure after a heart attack
  • Prevention of worsening kidney problems in some patients

Tritace may also be used to reduce the risk of cardiovascular problems and complications in patients aged 55 years or more with:

  • Heart disease caused by poor blood flow in the blood vessels of the heart , poor circulation in the hands or feet, or stroke
  • Patients with diabetes and with the following conditions that are considered at risk: high blood pressure, high cholesterol levels, kidney problem, a current smoker, or previous disease of the blood vessels.

Action

Tritace belongs to a group of medicines called ACE inhibitors. It works by widening the blood vessels, which results in the decrease of pressure in the blood vessels, helping to make it easier for your heart to pump blood. Hence, this increases the oxygen supply to your heart.

Also, by increasing the oxygen supply to your heart, your heart does not have to work as hard, which may decrease the risk of further damage on your heart which could lead to a heart attack.

Tritace also improves blood circulation through the small blood vessels in the kidneys, which assists the kidney to work more efficiently. Thus, this helps to slow down the progression of kidney damage.

Dose advice

Your doctor will inform you of how many tablets or capsules you will need to take each day. This depends on your condition. Take Tritace only when prescribed by your doctor.


Your doctor will select a suitable dose of Tritace for you. You should follow all your doctor’s directions carefully. They may differ from the information below. The usual dose of Tritace is:

  • for high blood pressure, 2.5 mg to 10 mg per day.
  • for heart failure, 5 mg to 10 mg per day.
  • for kidney problems, 1.25 mg to 5 mg per day.
  • for cardiovascular risk, 2.5 mg to 10 mg per day.

Depending on your response, your doctor may adjust the dose.

  • This medicine should be swallowed whole with plenty of fluid at about the same time each day
  • This medicine may cause dizziness on standing. If you become dizzy, sit or lie down. In order to minimize the dizziness, get up gradually from sitting or lying
  • Do not take potassium supplements while you are taking this medicine unless your doctor tells you to
  • This medicine may affect mental alertness and / or coordination. If affected, do not drive a motor vehicle or operate machinery
  • If swelling of face, lips or tongue is experienced, seek medical advice from your doctor or pharmacist
  • This medicine can cause a persistent, dry cough in some people. If you are unsure of any symptoms that you have, seek medical advice from your doctor or pharmacist.
  • You should limit your consumption of food containing high amounts of potassium e.g apricots, potatoes.
  • You should have your blood pressure regularly checked especially during the start of treatment
  • You should be monitored for your kidney function and potassium levels while taking Tritace. Consult your doctor about this.
  • Continue taking your medicine for as long as your doctor tells you.

Use in children:

The safety and effectiveness of Tritace has not been established in children.

Schedule

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Common side effects

All medicines have side effects. Most commonly the side effects are minor however some can be more serious. Usually the benefits of taking a medication outweigh the associated side effects. Your Doctor would have considered these side effects before starting you on Tritace.

Common side effects are those which occur in more than 1% of patients given Tritace. These include:


  • feeling faint, dizzy or light-headed
  • dry cough
  • headache
  • feeling sick (nausea) or vomiting
  • unusual tiredness or weakness, fatigue

Uncommon side effects

Side effects which occur in less than 1% of patients given Tritace are considered uncommon. Patients do not necessarily experience any of these side effects do not become alarmed by this list:

  • stomach pain
  • diarrhea
  • ringing or buzzing in the ears
  • forgetfulness or confusion
  • disturbed vision
  • symptoms of sunburn (e.g redness, itching, swelling, blistering) which could occur faster than normal
  • itchy or raised skin rash, hives
  • signs of anemia such as tiredness, short of breath and looking pale
  • yellowing of the skin and/or eyes
  • fast or irregular heart beat
  • tightness in the chest
  • tingling, numbness and change of color (white, blue then red) in the fingers or toes when exposed to the cold
  • frequent infections such as fever, severe chills, sore throat or mouth ulcers
  • passing little or no urine or more urine than normal
  • bleeding or bruising more easily than normal

If you experience any of these side effects or any other symptoms which are unusual please tell your doctor as soon as possible.

References

  1. Australian Medicines Handbook 2007, Adelaide, Pharmaceutical Society of Australia, 2007.
  2. MIMS Online. [Monograph online] MIMS Australia Pty Ltd 2003. [Cited May 21, 2008]. Available from: [URL Link]

For further information talk to your doctor.


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Dates

Posted On: 22 July, 2003
Modified On: 19 March, 2016
Reviewed On: 26 May, 2008


Created by: myVMC