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Rulide

Generic Name: Roxithromycin
Product Name: Rulide

Indication

Adults

  • Used for the treatment of mild to moderate infections caused by or likely to be caused by pathogens susceptible to Roxithyromycin
  • Upper respiratory tract infections: acute pharyngitis, tonsillitis, sinusitis.
  • Lower respiratory tract infections: acute bronchitis, acute exacerbations of chronic bronchitis, community acquired pneumonia
  • Skin and connective tissue infections
  • Non-gonococcal urethritis.

Children

  • Used for the treatment of mild to moderate infections caused by or likely to be caused by pathogens susceptible to Roxithromycin. (e.g. Acute pharyngitis, acute tonsillitis, impetigo)

Action

Roxithromycin is a semisynthetic macrolide antibiotic. It has a half life of 12 hours in healthy adults, 27 hours in elderly patients and 20 hours in children. Its breakdown is slowed by poor kidney and liver function. It is eliminated in the body from the faeces, urine and from the lungs

Dose advice

Adults

  • Most indications:
  • Rulide 300 mg tablets: one tablet daily, OR
  • Rulide 150 mg tablets: one tablet twice daily, or two tablets once daily
  • Atypical pneumonia: Roulide 150 mg: one tablet twice daily.

Children

  • Recommended routine: 5-8 mg/kg/day, administered twice daily as divided doses.
  • 6-11 kg: Half a Rulide D 50 mg tablet, twice daily
  • 12-23 kg: One Rulide D 50 mg tablet, twice daily
  • 24-40 kg: Two Rulide D 50 mg tablets, twice daily.

Schedule

S4

Common side effects

Roxithromycin is generally well tolerated

  • Nausea
  • Vomiting
  • Diarrhoea
  • Epigastric pain
  • Flatulence
  • Headache
  • Dizziness
  • Malaises
  • Moniliasis (candidiasis)
  • Hypersensitivity (urticaria, rash, pruritus, angioedema)

Uncommon side effects

Moderate increases in serum transaminases, more likely in the elderly

For further information talk to your doctor.

Dates

Posted On: 22 July, 2003
Modified On: 1 January, 1970

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Created by: myVMC