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Generic Name: Metoprolol tartrate
Product Name: Metohexal


-Hypertension-Angina-Tachyarrhythmias-Myocardial infarction-Prevention of migraine


Atenolol, a type of beta-1-selective-beta-Blocker, competitively blocks beta- adrenoceptors in the heart, peripheral vasculature, bronchi, pancreas, uterus, kidney, brain and liver.The antihypertensive effect works by reducing cardiac output without reflex increase in peripheral vascular resistance; CNS effect and reduced renin secretionmay also contribute.The antianginal effect is due to reductionin left ventricular work and oxygen use, resulting from decrease in heart rate and contractility.The antiarrhythmic properties are due to antisympathetic effects: depression of sinus node function and atrio-ventricular conduction and prolongation of atrial refractory periods.Atenolol, a beta-1-selective blocker, has a higher affinity for beta-1 receptors in the heart with less effect on beta-2 receptorsin bronchi and peripheral vasculature.

Dose advice

-Hypertension:Oral: initially 50-100mg once daily for 1 Week; maintenance 50-100mg once or twice daily-Angina:Oral: initially 25-50mg twice daily; maintenance 50-100mg 2-3 times daily-Tachyarrhthmias:Oral: 50-100mg 2-3 times dailyIV: 5mg (1mg/minute), repeated at 5 Minute intervals up to a maximum of 20mg-Myocardial infarction:Initially, IV 5mg at 5 minute intervals to a total of 15mg, then 25-50mg orally every 6 hours for 48 hours -Prevention of migraine:Oral: 50-75mg twice daily



Common side effects

-Nausea-Diarrhoea-Bronchospasm-Dyspnoea-Cold extremities-Exacerbation of Raynaud’s Syndrome-Bradycardia-Hypotension-Heart failure-Heart block-Fatigue-Dizziness-Abnormal vision-Decreased concentration-Hallucinations-Insomnia-Nightmares-Depression-Altered glucose and lipid metabolism

Uncommon side effects

-Rash-Exacerbation of psoriasis-Impotence-Muscle cramp-Acute urinary retention-Nasal congestion-Hypersensitivity reaction-Thrombocytopenic purpura-Liver function abnormality-Alopecia-Cardiac arrest-Hepatic injury


For further information talk to your doctor.


Posted On: 22 July, 2003
Modified On: 30 January, 2014

Created by: myVMC