Generic Name: Metoprolol tartrate
Product Name: Metohexal
Indication of Metohexal
-Hypertension-Angina-Tachyarrhythmias-Myocardial infarction-Prevention of migraine
Action of Metohexal
Atenolol, a type of beta-1-selective-beta-Blocker, competitively blocks beta- adrenoceptors in the heart, peripheral vasculature, bronchi, pancreas, uterus, kidney, brain and liver.The antihypertensive effect works by reducing cardiac output without reflex increase in peripheral vascular resistance; CNS effect and reduced renin secretionmay also contribute.The antianginal effect is due to reductionin left ventricular work and oxygen use, resulting from decrease in heart rate and contractility.The antiarrhythmic properties are due to antisympathetic effects: depression of sinus node function and atrio-ventricular conduction and prolongation of atrial refractory periods.Atenolol, a beta-1-selective blocker, has a higher affinity for beta-1 receptors in the heart with less effect on beta-2 receptorsin bronchi and peripheral vasculature.
Dose advice of Metohexal
-Hypertension:Oral: initially 50-100mg once daily for 1 Week; maintenance 50-100mg once or twice daily-Angina:Oral: initially 25-50mg twice daily; maintenance 50-100mg 2-3 times daily-Tachyarrhthmias:Oral: 50-100mg 2-3 times dailyIV: 5mg (1mg/minute), repeated at 5 Minute intervals up to a maximum of 20mg-Myocardial infarction:Initially, IV 5mg at 5 minute intervals to a total of 15mg, then 25-50mg orally every 6 hours for 48 hours -Prevention of migraine:Oral: 50-75mg twice daily
Schedule of Metohexal
Common side effects of Metohexal
-Nausea-Diarrhoea-Bronchospasm-Dyspnoea-Cold extremities-Exacerbation of Raynaud’s Syndrome-Bradycardia-Hypotension-Heart failure-Heart block-Fatigue-Dizziness-Abnormal vision-Decreased concentration-Hallucinations-Insomnia-Nightmares-Depression-Altered glucose and lipid metabolism
Uncommon side effects of Metohexal
-Rash-Exacerbation of psoriasis-Impotence-Muscle cramp-Acute urinary retention-Nasal congestion-Hypersensitivity reaction-Thrombocytopenic purpura-Liver function abnormality-Alopecia-Cardiac arrest-Hepatic injury
For further information talk to your doctor.