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Lanoxin

Generic Name: Digoxin
Product Name: Lanoxin

Indication

Digoxin is used in the treatment of:

  • Atrial fibrillation
  • Atrial flutter
  • Supraventricular tachycardia
  • Heart failure.

    Action

    Digoxin acts by increasing the force the heart muscle contracts with increasing the effectiveness of its pumping mechanism.It also slows the electrical conduction through the heart, which helps to prevent abnormal heart rhythms.

    Dose advice

    Doses should be tailored according to the individual patients renal function, clinical response and therapeutic drug monitoring.Adults:

  • Loading doses of 250-500 micrograms given orally or intravenously every 4-6 hours up to a maximum of 1.5 mg.
  • Maintenance dosing is 125-250 micrograms orally once daily.Children:
  • For children up to 2 years of age a loading dose of 30-40 micrograms/kg is given orally or intravenously.
  • For children older than 2 years of age a loading dose of 30 micrograms/kg is given orally or intravenously.
  • Half of the loading dose is given initially, then a quarter of the dose is given at 6-12 hours and the last quarter at 12-18 hours.
  • Maintenance dosing is 5-10 micrograms/kg orally per day given in 1 or 2 doses up to a maximum of 250 micrograms daily.Elderly patients:
  • Loading doses of 125-250 micrograms given orally or intravenously every 4-6 hours up to a maximum of 500 micrograms.
  • Maintenance dosing is 62.5-125 micrograms orally once daily.

    Schedule

    S4

    Common side effects

  • Loss of appetite
  • Nausea
  • Vomiting
  • Diarrhoea
  • Blurred vision
  • Confusion
  • Drowsiness
  • Dizziness
  • Nightmares
  • Agitation
  • Depression

    Uncommon side effects

  • Psychosis
  • Delirium
  • Amnesia
  • Development of breast tissue in males
  • Abnormal heart rhythms
  • Yellow vision

     

    For further information talk to your doctor.

  • Dates

    Posted On: 22 July, 2003
    Modified On: 30 January, 2014


    Created by: myVMC
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