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Bicor

Generic Name: Bisoprolol fumarate
Product Name: Bicor

Indication

Bisoprolol is used in the treatment of stable chronic moderate to severe heart failure. It is used in combination with other medication such as ACE inhibitors, diuretics and cardiac glycosides.

Action

Bisoprolol blocks beta-1 adrenoceptors in the heart and by doing this is reduces heart rate, reduces cardiac output and lowers the blood pressure.

Dose advice

Patients with stable chronic heart failure should be being treated with optimal doses of an ACE inhibitor, a diuretic, and possibly a cardiac glycoside before bisoprolol is considered as a treatment option. The dose of bisoprolol is gradually increased over weeks starting at 1.25 mg once daily to a maximum of 10 mg once daily. The dosage the patient takes should the dose prescribed to them by their doctor.When first staring treatment the patient needs to be monitored closely in case any side effects occur. Side effects may also prevent a patient from being treated with the maximum recommended dosage.Treatment with bisoprolol is generally long-term and it is recommended that bisoprolol is not stopped abruptly as this may lead to temporary worsening of the patient’s heart failure.

Schedule

S4

Common side effects

  • Cold and/or numb sensation in the extremities.
  • Fatigue
  • Dizziness
  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation

    Uncommon side effects

  • Muscle weakness
  • Muscle cramps
  • Bradycardia
  • Worsening of heart failure
  • Postural hypotension
  • Sleep disturbances
  • Depression
  • Bronchospasm in patients with bronchial asthma or a history of obstructive airways disease
  • Nightmares
  • Hallucinations
  • Rash
  • Increased liver enzymes (ALT, AST)
  • Hepatitis
  • Increased triglycerides
  • Impotence
  • Hearing impairment
  • Allergic rhinitis
  • Reduced tear flow
  • Exacerbation of psoriasis
  • Alopecia

     

    For further information talk to your doctor.

  • Dates

    Posted On: 22 July, 2003
    Modified On: 30 January, 2014


    Created by: myVMC