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Betaloc

Generic Name: Metoprolol tartrate
Product Name: Betaloc

Indication

Oral metoprolol is used in the treatment of high blood pressure, angina pectoris, myocardial infarction and as prophylaxis for migraines.Intravenous therapy: Metoprolol can be given intravenously to treat abnormal heart rhythms.

Action

Metoprolol acts on beta-adrenoreceptors present in the heart slowing the heart rate and decreasing the amount of work the heart has to do. It reduces blood pressure, reduces the frequency of angina attacks and has also been shown to reduce mortality in patients who have had a myocardial infarction by mechanisms that are not completely understood. In patients with abnormal heart rhythms, metoprolol has a regulating effect on the heart rate. Metoprolol has been shown to exert a prophylactic effect in both classical and common migraine.

Dose advice

Take Metoprolol as authorized by your doctor.

  • Hypertension (high blood pressure)Initial treatment:
  • Mild hypertension: One 50 mg tablet or one 100 mg tablet is given once a day for one week.
  • Severe hypertension: One 50 mg tablet or one 100 mg tablet twice a day for one week.After the first week one 50 mg tablet or one 100 mg tablet should be given either once or twice daily.The maximum daily dose should not exceed 400 mg and no added benefits occur by giving doses greater than 200 mg.Angina:
  • One 50 mg tablet or one 100 mg tablet given two or three times a day.Myocardial infarction:
  • Initially treatment is Betaloc 50 mg tablets twice a day and this should be continued for 48 hours. After this a 100 mg tablet should be taken twice daily.Intravenous Metoprolol can be given however this must be administered by experienced staff with close monitoring.Migraine prophylaxis
  • 100 to 150 mg is given in two divided doses – one in the morning and one in the evening.

    Schedule

    S4

    Common side effects

  • Gastrointestinal upsets
  • Sleep disturbances
  • Bradycardia
  • Postural disorders
  • Raynaud’s phenomenon
  • Palpitations
  • Fatigue
  • Dizziness
  • headache
  • Nausea
  • Diarrhoea
  • Constipation
  • Abdominal pain
  • Dyspnoea on exertion

    Uncommon side effects

  • Deterioration of heart failure symptoms
  • Heart block
  • Oedema
  • Precordial pain
  • Cardiac conduction disturbances
  • Cardiac arrhythmias
  • Gangrene in patients with pre-existing severe peripheral circulatory disorders
  • Paraesthesia
  • Muscle cramps
  • Vomiting
  • Dry mouth
  • Thrombocytopenia
  • Liver function test abnormalities
  • Hepatitis
  • Weight gain
  • Depression
  • Impaired concentration
  • Nervousness and anxiety
  • Sexual dysfunction
  • Memory impairment
  • Confusion
  • Hallucinations
  • Bronchospasm
  • Rhinitis
  • Disturbances of vision
  • Dry irritated eyes
  • Tinnitus
  • Taste disturbances
  • Rash
  • Increased sweating
  • Alopecia
  • Photosensitivity reactions
  • Arthralgia
  • Syncope

     

    For further information talk to your doctor.

  • Dates

    Posted On: 22 July, 2003
    Modified On: 13 March, 2014


    Created by: myVMC
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